| Identification | Back Directory | [Name]
LY-573636 | [CAS]
519055-63-1 | [Synonyms]
CS-881
LY 573636Na
Tasisulam sodium
Tasisulam Sodium (LY573636)
LY-573636 ISO 9001：2015 REACH
N-[(5-Bromo-2-thienyl)sulfonyl]-2,4-dichlorobenzamide sodium salt | [Molecular Formula]
C11H6BrCl2NO3S2.Na | [MDL Number]
MFCD11973637 | [MOL File]
519055-63-1.mol | [Molecular Weight]
437.092 |
| Hazard Information | Back Directory | [Uses]
Tasisulam is a anticancer agent and induces apoptosis via the intrinsic pathway, resulting in cytochrome c release and caspase-dependent cell death. Tasisulam inhibits mitotic progression and induces vascular normalization[1]. | [References]
[1] Meier T, et al. Tasisulam sodium, an antitumor agent that inhibits mitotic progression and induces vascular normalization. Mol Cancer Ther. 2011 Nov;10(11):2168-78. DOI:10.1158/1535-7163.MCT-11-0323 |
|
|