| Identification | Back Directory | [Name]
4,4''-DICYANOSTILBENE | [CAS]
5216-37-5 | [Synonyms]
4-[2-(4-cyanophenyl)vinyl]benzonitrile
Benzonitrile, 4,4'-(1E)-1,2-ethenediylbis- | [Molecular Formula]
C16H10N2 | [MDL Number]
MFCD00438701 | [MOL File]
5216-37-5.mol | [Molecular Weight]
230.26 |
| Hazard Information | Back Directory | [Uses]
4,4'-Dicyanostilbene (compound 43) is a potent antimalarial agent against the Dd2 strain, with an EC50 of 27 nM. 4,4'-Dicyanostilbene exhibits in vivo efficacy against methicillin-resistant Staphylococcus aureus (MRSA)[1]. | [References]
[1] Kyei-Baffour K, et, al. Natural product-inspired aryl isonitriles as a new class of antimalarial compounds against drug-resistant parasites. Bioorg Med Chem. 2020 Oct 1;28(19):115678. DOI:10.1016/j.bmc.2020.115678 |
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