ChemicalBook--->CAS DataBase List--->522-11-2

522-11-2

522-11-2 Structure

522-11-2 Structure
IdentificationBack Directory
[Name]

EUDESMINE
[CAS]

522-11-2
[Synonyms]

Evoxin, Haploperine
(+)-1-[(4,8-Dimethoxyfuro[2,3-b]quinolin-7-yl)oxy]-3-methyl-2,3-butanediol
2,3-Butanediol,1-[(4,8-dimethoxyfuro[2,3-b]quinolin-7-yl)oxy]-3-methyl-, (2R)-
[Molecular Formula]

C18H21NO6
[MDL Number]

MFCD31933596
[MOL File]

522-11-2.mol
[Molecular Weight]

347.36
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
Safety DataBack Directory
[Safety Statements ]

22-24/25
Hazard InformationBack Directory
[Uses]

Evoxine (Haplophytin B) is a compound that selectively inhibits CO2-induced immunosuppression and has activity in inhibiting the expression of interleukin-6 and chemokine CCL2 in human THP-1 macrophages. Evoxine shows antimicrobial activity against a wide range of bacteria, especially performing well in minimum inhibitory concentration (MIC) tests against Escherichia coli, Bacillus subtilis, and Staphylococcus aureus. Evoxine extracts may find application in crude drug preparations in West Africa, provided that their in vivo toxicity results are negative[1].
[Definition]

ChEBI: Evoxine is an organonitrogen heterocyclic compound, an oxacycle and an organic heterotricyclic compound.
[References]

[1] Antimicrobial Furoquinoline Alkaloids from Vepris lecomteana (Pierre) Cheek & T. Heller (Rutaceae) DOI:10.3390/molecules23010013
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