ChemicalBook--->CAS DataBase List--->52432-72-1

52432-72-1

52432-72-1 Structure

52432-72-1 Structure
IdentificationBack Directory
[Name]

OXELADIN CITRATE
[CAS]

52432-72-1
[Synonyms]

Oxeladine
er,citrate(1:1)
oxeladinecitrate
OXELADIN CITRATE
OXELADIN CITRATE SALT
OXELADINCITRATE(FORR&DONLY)
oxeladin dihydrogen citrate
Oxeladin hydrogen citrate CRS
Oxeladincitrate/Oxeladinidihydrogencitras
alpha,alpha-diethyl-benzeneaceticaci2-(2-(diethylamino)ethoxy)ethylest
butyricacid,2-ethyl-2-phenyl-,2-(2-(diethylamino)ethoxy)ethylester,citrate
2-(2-(Diethylamino)ethoxy)ethyl 2-ethyl-2-phenylbutanoate 2-hydroxypropane-1,2,3-tricarboxylate
2-[2-(diethylamino)ethoxy]ethyl 2-ethyl-2-phenylbutanoate,2-hydroxypropane-1,2,3-tricarboxylic acid
2-[2-(Diethylamino)ethoxy]ethyl 2-ethyl-2-phenylbutanoate dihydrogen 2-hydroxypropane-1,2,3-tricarboxylate.
[EINECS(EC#)]

257-910-8
[Molecular Formula]

C26H41NO10
[MDL Number]

MFCD00027040
[MOL File]

52432-72-1.mol
[Molecular Weight]

527.6
Chemical PropertiesBack Directory
[Appearance]

White or almost white, crystalline powder.
[Melting point ]

90-91°
[storage temp. ]

Inert atmosphere,Room Temperature
[solubility ]

Freely soluble in water, slightly to very slightly soluble in ethyl acetate.
[form ]

neat
[color ]

White to off-white
[Major Application]

forensics and toxicology
pharmaceutical (small molecule)
[InChIKey]

KVKJFNUGVOFNGU-UHFFFAOYSA-N
[SMILES]

OC(=O)CC(O)(CC(O)=O)C(O)=O.CCN(CC)CCOCCOC(=O)C(CC)(CC)c1ccccc1
[Uses]

Cough suppressant.
Hazard InformationBack Directory
[Chemical Properties]

White or almost white, crystalline powder.
[in vivo]

Oxeladin (135 mg/kg/d, p.o. for 11 d) reduces the extent of infarct expansion in the subacute phase of stroke in rats[1].

Animal Model:Middle cerebral artery occlusion model rats[1]
Dosage:135 mg/kg/day
Administration:MCAO for 2 d, then Oral gavage (p.o.) for 11 d
Result:Significantly improved neurological function on days 3, 7, and 14 following MCAO, decreased final extent of infarct after 14 days. Increased the amount of mature brain-derived neurotrophic factor in the cerebral cortex 2, 6, and 24 h after single oral dose.
Safety DataBack Directory
[Hazard Codes ]

T
[Risk Statements ]

23/24/25
[Safety Statements ]

36/37/39-45
[RIDADR ]

UN 2811 6.1/PG 3
[WGK Germany ]

3
[RTECS ]

ET1760000
[Storage Class]

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
[Hazard Classifications]

Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Spectrum DetailBack Directory
[Spectrum Detail]

OXELADIN CITRATE(52432-72-1)1HNMR
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