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52438-21-8

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52438-21-8 Structure

52438-21-8 Structure
IdentificationBack Directory
[Name]

1-cinnamoylpyrrolidine
[CAS]

52438-21-8
[Synonyms]

Cinnamopyrrolidide
1-cinnamoylpyrrolidine
1-[(2E)-1-Oxo-3-phenyl-2-propenyl]pyrrolidine
2-Propen-1-one, 3-phenyl-1-(1-pyrrolidinyl)-, (2E)-
[Molecular Formula]

C13H15NO
[MOL File]

52438-21-8.mol
[Molecular Weight]

201.26
Chemical PropertiesBack Directory
[Melting point ]

123℃
[storage temp. ]

Store at -20°C
[solubility ]

Acetone: soluble; Chloroform: soluble; Dichloromethane: soluble; DMSO: soluble; Ethyl Acetate: soluble
[form ]

A solid
Hazard InformationBack Directory
[Uses]

1-Cinnamoylpyrrolidine (Compound 3), a crude extract prepared from Piper caninum, is a DNA strand scission agent, induces the relaxation of supercoiled pBR322 plasmid DNA[1]. 1-Cinnamoylpyrrolidine (Compound 4) inhibits platelet aggregation induced by PAF with an IC50 of 37.3 μM[2].
[Definition]

ChEBI: 1-Cinnamoylpyrrolidine is an olefinic compound. It is functionally related to a cinnamic acid.
[storage]

Store at -20°C
[References]

[1] Send toBioorg Med Chem.Ma J, et al. Phenolic acid amides: a new type of DNA strand scission agent from Piper caninum. Bioorg Med Chem. 2004 Jul 15;12(14):3885-9. DOI:10.1016/j.bmc.2004.05.007
[2] Chen IS, et al. Amides with anti-platelet aggregation activity from Piper taiwanense. Fitoterapia. 2007 Sep;78(6):414-9. Epub 2007 May 24. DOI:10.1016/j.fitote.2007.04.009
Spectrum DetailBack Directory
[Spectrum Detail]

1-cinnamoylpyrrolidine(52438-21-8)1HNMR
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