| Identification | Back Directory | [Name]
Penicillin | [CAS]
525-94-0 | [Synonyms]
Adicillin
NSC113137
NSC-113137
NSC 113137
penicillin N
Synnematin B
Cephalosporin N
Adicillin impurity
Cefmenoxime Impurity 42
Benzylpenicillin Impurity 30
Benzylpenicillin Impurity 14 (Penicillin N)
6α-[[(R)-5-Amino-5-carboxy-1-oxopentyl]amino]penicillanic acid
(6R)-6-[[(R)-5-Amino-5-carboxy-1-oxopentyl]amino]penicillanic acid
(2S,5R,6R)-6-[[(5R)-5-amino-5-carboxy-pentanoyl]amino]-3,3-dimethyl-7- oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(5R)-5-amino-5-carboxy-1-oxopentyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)- | [Molecular Formula]
C14H21N3O6S | [MDL Number]
MFCD00864904 | [MOL File]
525-94-0.mol | [Molecular Weight]
359.401 |
| Hazard Information | Back Directory | [Uses]
Penicillin N (Adicillin) is a penicillin-type compound used to inhibit enteric bacilli infections. | [Definition]
ChEBI: Penicillin N is a penicillin. It is a conjugate acid of a penicillin N(1-). | [Enzyme inhibitor]
This antibiotic (FWfree-acid = 359.40 g/mol; CAS 525-94-0; Water-soluble), also known as (2S,5R,6R)-6-[[(5R)-5-amino-5-carboxy-1-oxopentyl]amino] -3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, (D-4-amino-4-carboxybutyl)-penicillinic acid, Adicillin?, Synnematin B?, as well as cephalosporin N, is produced by species of Cephalosporium as well as by Paecilomyces percicimus and Penicillium chrysogenum. (For details on mode of action, See Penicillins) Spectrum of Antibiotic Action: Penicillin N bacteriocida against Diplococcus pneumoniae, Proteus vulgaris, Salmonella typhimurium, Sarcina lutea, but shows little no activity against Bacillus subtilis and Staphylococcus aureus. Target(s): deacetoxycephalosporin-C hydroxylase; and deacetylcephalosporin-C acetyltransferase. | [References]
[1] Penicillin N therapy of enteric bacillary infections |
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