ChemicalBook--->CAS DataBase List--->52869-18-8

52869-18-8

52869-18-8 Structure

52869-18-8 Structure
IdentificationBack Directory
[Name]

N-(9,10-dioxo-9,10-dihydroanthracen-2-yl)benzamide
[CAS]

52869-18-8
[Synonyms]

SSAA09E3
N-(9,10-dioxo-9,10-dihydroanthracen-2-yl)benzamide
[EINECS(EC#)]

660-768-3
[Molecular Formula]

C21H13NO3
[MDL Number]

MFCD00157867
[MOL File]

52869-18-8.mol
[Molecular Weight]

327.333
Chemical PropertiesBack Directory
[storage temp. ]

4°C, protect from light
[form ]

Solid
[color ]

Light brown to brown
Safety DataBack Directory
[Symbol(GHS) ]


GHS09
[Signal word ]

Warning
[Hazard statements ]

H410
[Precautionary statements ]

P273-P391-P501
Hazard InformationBack Directory
[Description]

SSAA09E3 is a novel inhibitor of SARS-CoV replication, acting by preventing fusion of the viral membrane with the host cellular membrane.
[Uses]

SSAA09E3 is a SARS-CoV entry inhibitor that inhibits SARS/HIV pseudotyped virus entry with an EC50 of 9.7 μM in 293T cells and inhibits SARS-CoV infection of Vero cells with an EC50 of 0.15 μM[1][2].
[storage]

4°C, protect from light
[References]

[1] Ghosh AK, et al. Drug Development and Medicinal Chemistry Efforts toward SARS-Coronavirus and Covid-19 Therapeutics. ChemMedChem. 2020 Jun 4;15(11):907-932. DOI:10.1002/cmdc.202000223
[2] Adedeji AO, et al. Novel inhibitors of severe acute respiratory syndrome coronavirus entry that act by three distinct mechanisms. J Virol. 2013 Jul;87(14):8017-28. DOI:10.1128/JVI.00998-13
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