| Identification | Back Directory | [Name]
suksdorfin | [CAS]
53023-17-9 | [Synonyms]
suksdorfin
(9R,10R)-9-acetoxy-8,8-dimethyl-2-oxo-2,8,9,10-tetrahydropyrano[2,3-f]chromen-10-yl 3-methylbutanoate
3-Methylbutanoic acid [(9R,10R)-9-acetoxy-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-10-yl] ester | [Molecular Formula]
C21H24O7 | [MOL File]
53023-17-9.mol | [Molecular Weight]
388.414 |
| Hazard Information | Back Directory | [Description]
Suksdorfin is a acylated khellactone isolated from the fruit of Lomatium suksdorfii that was found to be able to inhibit HIV-1 replication. | [Uses]
Suksdorfin is a compound isolated from the fruits of Lomatium suksdorfii. Suksdorfin has activity againstHIV-1[1]. | [References]
[1] Lee TT, et al. Suksdorfin: an anti-HIV principle from Lomatium suksdorfii, its structure-activity correlation with related coumarins, and synergistic effects with anti-AIDS nucleosides. Bioorg Med Chem. 1994 Oct;2(10):1051-6. DOI:10.1016/s0968-0896(00)82054-4 |
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