| Identification | Back Directory | [Name]
2H-Isoindole-2-acetamide, 1,3-dihydro-N-[4-(3-methoxyphenyl)-2-thiazolyl]-1,3-dioxo- | [CAS]
536731-65-4 | [Synonyms]
GSK-3β inhibitor 11
2-(1,3-Dioxoisoindolin-2-yl)-N-(4-(3-methoxyphenyl)thiazol-2-yl)acetamide
2H-Isoindole-2-acetamide, 1,3-dihydro-N-[4-(3-methoxyphenyl)-2-thiazolyl]-1,3-dioxo- | [Molecular Formula]
C20H15N3O4S | [MOL File]
536731-65-4.mol | [Molecular Weight]
393.42 |
| Chemical Properties | Back Directory | [density ]
1.440±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
7.99±0.50(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Description]
GSK-3β inhibitor 11 (compound 21) is a glycogen synthase kinase-3β (GSK-3β) inhibitor (IC50=10.02 μM). GSK-3β inhibitor 11 can be used in neurodegenerative disease research[1]. | [Uses]
GSK-3β inhibitor 11 (compound 21) is a glycogen synthase kinase-3β (GSK-3β) inhibitor (IC50=10.02 μM). GSK-3β inhibitor 11 can be used in neurodegenerative disease research[1]. | [IC 50]
GSK-3β: 10.02 μM (IC50) | [References]
[1] Fu G, et al. Pharmacophore Modeling, Ensemble Docking, Virtual Screening, and Biological Evaluation on Glycogen Synthase Kinase-3β. Mol Inform. 2014 Sep;33(9):610-26. DOI:10.1002/minf.201400044 |
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