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53764-90-2

53764-90-2 Structure

53764-90-2 Structure
IdentificationBack Directory
[Name]

9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, ISOPROPYL ESTER
[CAS]

53764-90-2
[Synonyms]

FPABVZYYTCHNMK-YNRDDPJXSA-N
prostaglandin F2 isopropyl ester
Prostaglandin F2α isopropyl ester
PROSTAGLANDIN F2ALPHA ISOPROPYL ESTER
9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, ISOPROPYL ESTER
Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, 1-methylethyl ester, (5Z,9α,11α,13E,15S)-
[Molecular Formula]

C23H40O5
[MDL Number]

MFCD00135232
[MOL File]

53764-90-2.mol
[Molecular Weight]

396.56
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: >30 mg/ml; DMSO: >50 mg/ml; Ethanol: >50 mg/ml; PBS pH 7.2: <50 μg/ml
Safety DataBack Directory
[Symbol(GHS) ]


GHS02,GHS07,GHS08
[Signal word ]

Danger
[Hazard statements ]

H225-H319-H360-H336
[Precautionary statements ]

P201-P202-P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P308+P313-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501
Hazard InformationBack Directory
[Uses]

PGF2α-isopropyl ester is a Prostaglandin F2α (HY-12956) derivative, which is active in lowering the intraocular pressure (IOP) through increased uveoscleral outflow of aqueous humor. PGF2α-isopropyl ester causes side effects of conjunctival hyperemia and ocular irritation[1].
[Definition]

ChEBI: PGF2alpha isopropyl ester is a prostanoid.
[References]

[1] Stjernschantz JW. From PGF(2alpha)-isopropyl ester to latanoprost: a review of the development of xalatan: the Proctor Lecture. Invest Ophthalmol Vis Sci. 2001 May;42(6):1134-45. PMID:11328719
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