| Identification | Back Directory | [Name]
Ethyl trans-3-(1-pyrrolidino)acrylate | [CAS]
53927-12-1 | [Synonyms]
Ethyl 1- pyrrolidine acrylate
Ethyl b-(1-Pyrrolidinyl)acrylate
1-Pyrrolidineacrylic acid ethyl ester
3-(1-pyrrolidinyl)-2-propenoic acid ethyl ester
2-Propenoic acid, 3-(1-pyrrolidinyl)-, ethyl ester | [Molecular Formula]
C9H15NO2 | [MOL File]
53927-12-1.mol | [Molecular Weight]
169.22 |
| Chemical Properties | Back Directory | [Melting point ]
mp 41-43 °C | [Boiling point ]
bp 80-105 °C/10-3 mmHg | [solubility ]
sol most organic solvents (ethanol, ethyl acetate, dichloromethane, chloroform, THF) |
| Hazard Information | Back Directory | [Uses]
Ethyl trans-3-(1-pyrrolidino)acrylate is used as a precursor to β-vinyllithium derivative; reactions with electrophiles yield cyclopentenones, butenolides, maleic acid derivatives, and oxalacetic acid derivatives.
| [Synthesis Reference(s)]
1. Grinblat, E. I.; Postovski?, I. Y. DOK 1960, 133, 847.
2. Kanner, C. B.; Pandit, U. K. T 1982, 38, 3597.
| [Synthesis]
Ethyl trans-3-(1-pyrrolidino)acrylate is synthesized by reaction of ethyl propiolate with pyrrolidine in acetonitrile at rt yields ethyl β-(1- pyrrolidinyl)acrylate in 55% yield as a colorless solid.1,2
| [storage]
Ethyl trans-3-(1-pyrrolidino)acrylate can be stored under nitrogen protected from moisture.
| [Purification Methods]
Ethyl trans-3-(1-pyrrolidino)acrylate distills under reduced pressure.
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