ChemicalBook--->CAS DataBase List--->54-80-8

54-80-8

54-80-8 Structure

54-80-8 Structure
IdentificationBack Directory
[Name]

Pronetalol
[CAS]

54-80-8
[Synonyms]

Inetol
Alderlin
Nethalide
Pronetalol
pronethalol
Pronethanol
Naphthylisoproterenol
2-(isopropylamino)-1-(2-naphthyl)ethanol
(+/-)-1-(2'-Naphthyl)-2-isopropylaMinoethanol
1-naphthalen-2-yl-2-(propan-2-ylamino)ethanol
α-[(Isopropylamino)methyl]-2-naphthalenemethanol
α-[(tert-Butylamino)methyl]-2-naphthalenemethanol
α-[[(1-Methylethyl)amino]methyl]naphthalene-2-methanol
α-[[(1-Methylethyl)aMino]Methyl]-2-naphthaleneMethanol
[Molecular Formula]

C15H19NO
[MOL File]

54-80-8.mol
[Molecular Weight]

229.321
Chemical PropertiesBack Directory
[Melting point ]

108°
[Boiling point ]

371.23°C (rough estimate)
[density ]

1.0020 (rough estimate)
[refractive index ]

1.5200 (estimate)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

13.91±0.20(Predicted)
[color ]

White to off-white
[CAS DataBase Reference]

54-80-8
Hazard InformationBack Directory
[Uses]

A non-selective beta blocker, not yet used in treatment due to carcinogenic properties.
[Uses]

beta adrenergic agonist, antiarrhythmic
[Definition]

ChEBI:Pronethalol is a member of naphthalenes.
[in vivo]

Pronethalol (0.15 mg/g; daily; for 14 days) stabilizes endothelial differentiation, lumen formation and improves cerebral arteriovenous malformation (AVMs) in Mgp–/– mice[2].

[IC 50]

β adrenergic receptor
[storage]

Store at -20°C
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