| Identification | Back Directory | [Name]
2-hydroxy-1-naphthalaldehyde salicyloylhydrazone | [CAS]
54009-54-0 | [Synonyms]
2-hydroxy-1-naphthalaldehyde salicyloylhydrazone
Benzoic acid, 2-hydroxy-, 2-[(2-hydroxy-1-naphthalenyl)methylene]hydrazide | [Molecular Formula]
C18H14N2O3 | [MOL File]
54009-54-0.mol | [Molecular Weight]
306.32 |
| Hazard Information | Back Directory | [Uses]
(E/Z)-NSAH is an isoform of NSAH (HY-114503), which is reversible and competitive nonnucleoside ribonucleotide reductase (RR) inhibitor, with cell-free IC50 of 32 μM and cell-based IC50 of ~250 nM, respectively[1]. | [References]
[1] Md Faiz Ahmad, et al. Potent competitive inhibition of human ribonucleotide reductase by a nonnucleoside small molecule. Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):8241-8246. DOI:10.1073/pnas.1620220114 |
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