| Identification | Back Directory | [Name]
(3-BENZYLOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE | [CAS]
54314-85-1 | [Synonyms]
3-benzyloxypropyl(triphenyl)phosphonium
triphenyl(3-phenylmethoxypropyl)phosphanium
(3-BENZYLOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE
(3-Benzyloxypropyl)triphenylphosphonium bromide 98%
triphenyl(3-phenylmethoxypropyl)phosphanium,bromide
(3-Benzyloxypropyl)triphenylphosphonium bromide, 97+%
white to off-white powder | [Molecular Formula]
C28H28BrOP | [MDL Number]
MFCD00191781 | [MOL File]
54314-85-1.mol | [Molecular Weight]
491.4 |
| Chemical Properties | Back Directory | [Melting point ]
153-154 °C(lit.)
| [storage temp. ]
Store at room temperature | [form ]
Powder | [color ]
White to off-white | [InChI]
InChI=1S/C28H28OP.BrH/c1-5-14-25(15-6-1)24-29-22-13-23-30(26-16-7-2-8-17-26,27-18-9-3-10-19-27)28-20-11-4-12-21-28;/h1-12,14-21H,13,22-24H2;1H/q+1;/p-1 | [InChIKey]
DWYCJWXMZGVGJV-UHFFFAOYSA-M | [SMILES]
[P+](CCCOCC1=CC=CC=C1)(C1=CC=CC=C1)(C1C=CC=CC=1)C1C=CC=CC=1.[Br-] |
| Hazard Information | Back Directory | [Uses]
(3-Benzyloxypropyl)triphenylphosphonium Bromide is a reagent used in the preparation of antitumor and Her2 degradation activity of geldanamycin and radicicol macrocyclic chimeras. | [Uses]
Reactant for preparation of:
- Spirocyclohexadienones via Pd-catalyzed intramolecular ipso-Friedel-Crafts allylic alkylation
- Inhibitors of heat shock protein (Hsp90) as antitumor agents
- Carpanone-like molecules via an oxidative coupling/Diels-Alder cycloaddition sequence
| [reaction suitability]
reaction type: C-C Bond Formation |
|
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Alfa Aesar
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400-6106006 |
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Energy Chemical
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www.energy-chemical.com |
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T&W GROUP
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Sigma-Aldrich
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