| Identification | Back Directory | [Name]
16-PHENOXY TETRANOR PROSTAGLANDIN E2 | [CAS]
54382-74-0 | [Synonyms]
LYXKJZCRLQWIIN-BYCQWZGOSA-N
16-PHENOXY TETRANOR PROSTAGLANDIN E2
9-OXO-11ALPHA,15R-DIHYDROXY-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID | [Molecular Formula]
C22H28O6 | [MDL Number]
MFCD00797647 | [MOL File]
54382-74-0.mol | [Molecular Weight]
388.45 |
| Chemical Properties | Back Directory | [Boiling point ]
605.1±55.0 °C(Predicted) | [density ]
1.256±0.06 g/cm3(Predicted) | [solubility ]
DMF: 100 mg/ml; DMSO: 100 mg/ml; Ethanol: 100 mg/ml; PBS (pH 7.2): 0.8 mg/ml | [pka]
4.75±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
16-phenoxy tetranor PGE2 is the free acid form of sulprostone formed by the hydrolysis of the methylsulfonamide bond. 16-phenoxy tetranor PGE2 is a minor metabolite of sulprostone found in human plasma after parenteral administration of the drug. | [Uses]
16-phenoxy tetranor PGE2 is the free acid form of sulprostone formed by the hydrolysis of the methylsulfonamide bond.1 16-phenoxy tetranor PGE2 is a minor metabolite of sulprostone found in human plasma after parenteral administration of the drug. | [References]
[1] Kuhnz, et al. Identification of the major metabolites of the prostaglandin E2-analogue sulprostone in human plasma, and isolation from urine (in vivo) and liver perfusate (in vitro) of female guinea-pigs. Drug Metab. Dispos. 19(5), 920-925 (1991). |
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