| Identification | Back Directory | [Name]
MYRISTOLEIC ACID | [CAS]
544-64-9 | [Synonyms]
MYRISTOLEIC ACID
Myristolenic acid
C14:1 (CIS-9) ACID
9-tetradecenoic acid
MYRISTOLEIC ACID 99%
(z)-9-tetradecenoicaci
(Z)-9-Tetradecenoicacid
9-cis-Tetradecenoic acid
CIS-9-TETRADECENOIC ACID
(9Z)-9-Tetradecenoic acid
(Z)-tetradec-9-enoic acid
9-Tetradecenoic acid, (9Z)-
DELTA 9 CIS TETRADECENOIC ACID
Myristolenic acidTetradecenoic acid
Myristoleic acid >=99% (capillary GC)
Myristoleic acid,cis-9-Tetradecenoic acid | [EINECS(EC#)]
208-876-8 | [Molecular Formula]
C14H26O2 | [MDL Number]
MFCD00004436 | [MOL File]
544-64-9.mol | [Molecular Weight]
226.36 |
| Chemical Properties | Back Directory | [Appearance]
Colorless liquid. Found in fatof some seeds and in fish oil. | [Melting point ]
−4.5-−4 °C(lit.)
| [Boiling point ]
144 °C0.6 mm Hg(lit.)
| [density ]
0.9 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.4562(lit.)
| [Fp ]
62 °C | [storage temp. ]
−20°C
| [solubility ]
Benzene (Slightly), Chloroform (Slightly), Methanol (Slightly) | [form ]
Liquid | [pka]
4.78±0.10(Predicted) | [color ]
Colourless | [biological source]
plant | [Cosmetics Ingredients Functions]
NOT REPORTED | [InChI]
InChI=1S/C14H26O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16/h5-6H,2-4,7-13H2,1H3,(H,15,16)/b6-5- | [InChIKey]
YWWVWXASSLXJHU-WAYWQWQTSA-N | [SMILES]
C(O)(=O)CCCCCCC/C=C\CCCC | [LogP]
5.383 (est) | [EPA Substance Registry System]
9-Tetradecenoic acid, (9Z)- (544-64-9) |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless liquid. Found in fatof some seeds and in fish oil. | [Uses]
Myristoleic Acid induces apoptosis and necrosis in human prostrate cancer cell LNCaP, and is of a potential for developing an attractive new tool for the treatment of prostrate cancer. | [Definition]
ChEBI: Myristoleic acid is a tetradecenoic acid in which the double bond is at the 9-10 position and has Z configuration. Myristoleic acid has been isolated from Serenoa repens and has cytotoxic and apoptosis-inducing effects. It has a role as an apoptosis inducer, a plant metabolite and an EC 3.1.1.1 (carboxylesterase) inhibitor. It is a tetradecenoic acid and a long-chain fatty acid. It is a conjugate acid of a myristoleate. | [in vivo]
Myristoleic acid (2 mg/kg, IP every 24 h for 4 days) prevents RANKL-induced bone loss and osteoclast formation in mice[2].
| Animal Model: | C57BL/6 mice at 5 weeks[2].
| | Dosage: | 0.2, 2 mg/kg | | Administration: | IP every 24 h for 4 days. | | Result: | Co-administration of myristoleic acid suppressed generation of TRAP-positive osteoclasts induced by sRANKL and attenuated the increases in osteoclastic indices of Oc.S/BS, N.Oc/B. Pm and ES/BS in a dose-dependent manner. |
| [IC 50]
Human Endogenous Metabolite | [storage]
Store at -20°C |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
36/37/38 | [Safety Statements ]
26-36 | [RIDADR ]
NA 1993 / PGIII | [WGK Germany ]
3
| [TSCA ]
TSCA listed | [Storage Class]
10 - Combustible liquids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
|
|