| Identification | Back Directory | [Name]
9(Z),11(Z)-Conjugated Linoleic Acid | [CAS]
544-70-7 | [Synonyms]
9(Z),11(Z)-Conjugated Linoleic Acid
9,11-Octadecadienoic acid, (9Z,11Z)-
(9Z,11Z)-9,11-Octadecadienoic Acid (>85%) | [Molecular Formula]
C18H32O2 | [MDL Number]
MFCD02259039 | [MOL File]
544-70-7.mol | [Molecular Weight]
280.45 |
| Chemical Properties | Back Directory | [Melting point ]
44 - 45oC | [Boiling point ]
381.6±11.0 °C(Predicted) | [density ]
0.8802 g/cm3(Temp: 70 °C) | [storage temp. ]
Refrigerator, under inert atmosphere | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
4.78±0.10(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Description]
9(Z),11(Z)-Conjugated linoleic acid is an isomer of linoleic acid that has been found in milk from cows and other animals. It is cytotoxic to Caco-2 human colon cancer cells (EC50 = 446.1 μM) and induces changes in the miRNA profile, including an upregulation hsa-miR-146a-5p and downregulation of hsa-miR-32-5p, which is involved in apoptosis. [Matreya, LLC. Catalog No. 1248] | [Uses]
(9Z,11Z)-9,11-Octadecadienoic Acid, is a conjugated Linoleic Acid, a compound that has reported to exhibit anticarcinogenic activity. Linoleic Acid is an anti-inflammatory, acne reductive, and moisture retentive when applied topically on the skin. It is popular in the beauty products industry because of its beneficial properties on the skin. | [Definition]
ChEBI: 9Z,11Z-octadecadienoic acid is an octadecadienoic acid. | [References]
[1] MELISSA L. BAINBRIDGE . Milk from cows grazing on cool-season pastures provides an enhanced profile of bioactive fatty acids compared to those grazed on a monoculture of pearl millet[J]. Food Chemistry, 2017, 217: Pages 750-755. DOI: 10.1016/j.foodchem.2016.08.134
[2] I. REVILLA . Fatty acids and fat-soluble vitamins in ewe’s milk predicted by near infrared reflectance spectroscopy. Determination of seasonality[J]. Food Chemistry, 2017, 214: Pages 468-477. DOI: 10.1016/j.foodchem.2016.07.078
[3] SOLVEIGH K?PKE Alfonso L Thorsten Buhrke. miRNA Expression in Human Intestinal Caco-2 Cells is Comparably Regulated by cis- and trans-Fatty Acids[J]. Lipids, 2015, 50 3: 227-239. DOI: 10.1007/s11745-015-3988-x |
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Enzo Biochem Inc
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