ChemicalBook--->CAS DataBase List--->54432-43-8

54432-43-8

54432-43-8 Structure

54432-43-8 Structure
IdentificationBack Directory
[Name]

3-METHOXY PROSTAGLANDIN F1ALPHA
[CAS]

54432-43-8
[Synonyms]

3-methoxy Prostaglandin F1α
UBKBNBIEPZZFBF-XZFPMTPLSA-N
3-METHOXY PROSTAGLANDIN F1ALPHA
3-METHOXY-9ALPHA,11ALPHA,15S-TRIHYDROXY-PROST-13Z-EN-1-OIC ACID
Prost-13-en-1-oic acid, 9,11,15-trihydroxy-3-methoxy-, (9α,11α,13E,15S)- (9CI)
[Molecular Formula]

C21H38O6
[MDL Number]

MFCD02259331
[MOL File]

54432-43-8.mol
[Molecular Weight]

386.52
Chemical PropertiesBack Directory
[solubility ]

DMF: >23 mg/ml; DMSO: >33 mg/ml; Ethanol: >100 mg/ml; PBS pH 7.2: 16.7 mg/ml
Safety DataBack Directory
[Symbol(GHS) ]

Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
[Signal word ]

Danger
[Hazard statements ]

H225-H319-H336
[Precautionary statements ]

P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501
Hazard InformationBack Directory
[Description]

3-methoxy PGF is a novel analog of PGF with a methoxy group in the 3-position of the upper side chain. There are no published reports describing the pharmacology of 3-methoxy PGF at this time.
[Uses]

3-Methoxy prostaglandin F1α is an analog of PGF1α that can be metabolized by naturally occurring extracellular antibiotic resistance genes (eARGs) that enter the intestine via the food chain[1].
[Definition]

ChEBI: 3-Methoxy prostaglandin F1alpha is a prostanoid.
[References]

[1] Rong Tan, et al. Exogenous antibiotic resistance gene contributes to intestinal inflammation by modulating the gut microbiome and inflammatory cytokine responses in mouse. Gut Microbes. 2023 Jan-Dec;15(1):2156764. DOI:10.1080/19490976.2022.2156764
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