| Identification | Back Directory | [Name]
ent-PGF2α | [CAS]
54483-31-7 | [Synonyms]
ent-PGF2α
ent-Prostaglandin F2α
PXGPLTODNUVGFL-FCINMJCXSA-N
ent-Prostaglandin F2.alpha.
Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,8β,9β,11β,12α,13E,15R)- | [Molecular Formula]
C20H34O5 | [MDL Number]
MFCD12912278 | [MOL File]
54483-31-7.mol | [Molecular Weight]
354.48 |
| Hazard Information | Back Directory | [Description]
Enzymatically-derived Prostaglandin F2α (PGF2α) is an optically pure compound whereas PGF2α derived from the free radical-catalyzed peroxidation of arachidonate is a racemic mixture. Ent-PGF2α is the opposite enantiomer of PGF2α. This compound can only be generated via the isoprostane pathway of free radical-catalyzed lipid peroxidation and has been implicated as a marker of oxidative stress. Levels of ent-PGF2α are elevated in human urine from heavy cigarette smokers and patients with hypercholesterolemia. | [Uses]
ent-Prostaglandin F2α is the opposite enantiomer of PGF2α. ent-Prostaglandin F2α can be found in urine[1]. | [Definition]
ChEBI: Ent-PGF2alpha is a prostanoid. | [References]
[1] Yin H, et al. Urinary prostaglandin F2alpha is generated from the isoprostane pathway and not the cyclooxygenase in humans. J Biol Chem. 2007 Jan 5;282(1):329-36. DOI:10.1074/jbc.M608975200 |
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