| Identification | Back Directory | [Name]
Methanone, [2-(4-methylphenyl)-4-quinolinyl][4-(2-pyrimidinyl)-1-piperazinyl]- | [CAS]
546100-66-7 | [Synonyms]
WAY-350568
lucPpy-IN-1
(4-(Pyrimidin-2-yl)piperazin-1-yl)(2-(p-tolyl)quinolin-4-yl)methanone
Methanone, [2-(4-methylphenyl)-4-quinolinyl][4-(2-pyrimidinyl)-1-piperazinyl]- | [Molecular Formula]
C25H23N5O | [MOL File]
546100-66-7.mol | [Molecular Weight]
409.48 |
| Chemical Properties | Back Directory | [Boiling point ]
674.1±65.0 °C(Predicted) | [density ]
1.259±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
4.87±0.33(Predicted) | [color ]
Pink to orange |
| Hazard Information | Back Directory | [Uses]
lucPpy-IN-1 (compound 9) is an ATP-dependent luciferase from Photinus pyralis (lucPpy) inhibitor with an IC50 value of 4.0 μM. lucPpy-IN-1 can be used for the research of target’s agentgability[1]. | [References]
[1] Auld DS, et al. A basis for reduced chemical library inhibition of firefly luciferase obtained from directed evolution. J Med Chem. 2009 Mar 12;52(5):1450-8. DOI:10.1021/jm8014525 |
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