| Identification | Back Directory | [Name]
(4aα)-2-Methylene-5,5,8aβ-trimethyldecalin-1β-methanol | [CAS]
54632-04-1 | [Synonyms]
Albicanol
CCRIS8459
CCRIS-8459
CCRIS 8459
(+)-Albicanol
(4aα)-2-Methylene-5,5,8aβ-trimethyldecalin-1β-methanol
(4aα)-Decahydro-5,5,8aβ-trimethyl-2-methylenenaphthalene-1β-methanol
(1S,4aα)-Decahydro-5,5,8aβ-trimethyl-2-methylenenaphthalene-1-methanol | [Molecular Formula]
C15H26O | [MOL File]
54632-04-1.mol | [Molecular Weight]
222.37 |
| Chemical Properties | Back Directory | [Melting point ]
68-69 °C | [Boiling point ]
299.3±9.0 °C(Predicted) | [density ]
0.95±0.1 g/cm3(Predicted) | [pka]
14.86±0.10(Predicted) | [LogP]
4.661 (est) |
| Hazard Information | Back Directory | [Uses]
Albicanol is a sesquiterpenoid with potent antioxidant and antagonistic activities against heavy metal toxicity. Albicanol shows cytotoxicity. Albicanol suppress profenofos (HY-B0832) induced genotoxicity in grass carp hepatocytes[1][2]. | [Definition]
ChEBI: (+)-albicanol is a drimane-type sesquiterpenoid orginally isolated from the liverwort Diplophyllum albicans. It exhibits fish antifeedant, antifungal and antineoplastic activities. It has a role as an antifungal agent, a plant metabolite, an antineoplastic agent, a fungal metabolite, a mammalian metabolite, an antifeedant and a marine metabolite. It is a sesquiterpenoid, a primary alcohol, a homoallylic alcohol and a carbobicyclic compound. It derives from a hydride of a drimane. | [References]
[1] Zhao DD, et al. Compounds from Dryopteris fragrans (L.) Schott with cytotoxic activity. Molecules. 2014 Mar 18;19(3):3345-55. DOI:10.3390/molecules19033345
[2] Lihui X, et al. Albicanol modulates oxidative stress and the p53 axis to suppress profenofos induced genotoxicity in grass carp hepatocytes. Fish Shellfish Immunol. 2022 Mar;122:325-333. DOI:10.1016/j.fsi.2022.02.002 |
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