| Identification | Back Directory | [Name]
3',4'-DIHYDROXY-2-METHYLPROPIOPHENONE | [CAS]
5466-89-7 | [Synonyms]
U-0521
U-0521,98+%
U0521,U 0521
3’,4’-dihydroxy-isobutyrophenon
3’,4’-dihydroxyisobutyrophenone
3’,4’-dihydroxy-2-methyl-propiophenon
3',4'-DIHYDROXY-2-METHYLPROPIOPHENONE
3',4'-Dihydroxy-α-methylpropiophenone
1-(3,4-dihydroxyphenyl)-2-methyl-1-propanon
1-(3,4-Dihydroxyphenyl)-2-methylpropan-1-one
1-Propanone, 1-(3,4-dihydroxyphenyl)-2-methyl- | [Molecular Formula]
C10H12O3 | [MDL Number]
MFCD00211220 | [MOL File]
5466-89-7.mol | [Molecular Weight]
180.2 |
| Chemical Properties | Back Directory | [Melting point ]
79-81℃ | [Boiling point ]
372.2±27.0 °C(Predicted) | [density ]
1.191±0.06 g/cm3(Predicted) | [RTECS ]
NQ5605000 | [storage temp. ]
-20°C Freezer | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | [form ]
White solid. | [pka]
8.77±0.31(Predicted) | [color ]
Off-White to Pale Beige |
| Hazard Information | Back Directory | [Uses]
U-0521 is an extraneuronal COMT uptake inhibitor. | [Definition]
ChEBI: U 0521 is a member of acetophenones. | [in vivo]
U-0521 (i.p.; 0-250 mg/kg; 10 min) inhibits COMT activity in a dose-dependent manner. 50% inhibition of enzyme activity is obtained at 90 mg/kg and maximum inhibition of 90% is obtained at 250 mg/kg[1]. | Animal Model: | Male Sprague-Dawley rats (180-250 g)[1] | | Dosage: | 0-250 mg/kg | | Administration: | i.p.; 10 min | | Result: | Inhibited COMT activity in a dose-dependent manner. 50% inhibition of enzyme activity was obtained at 90mg/kg and maximum inhibition of 90% was obtained at 250 mg/kg. |
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| Company Name: |
Enzo Biochem Inc
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| Tel: |
Enzo Biochem Inc. 13797054060 |
| Website: |
www.enzo.com |
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