| Identification | Back Directory | [Name]
BenzenesulfonaMide, 4-Methyl-N-2-propyn-1-yl- | [CAS]
55022-46-3 | [Synonyms]
4-methyl-N-prop-2-ynylbenzenesulfonamide
4-methyl-N-(prop-2-yn-1-yl)benzenesulfonamide
BenzenesulfonaMide, 4-Methyl-N-2-propyn-1-yl-
4-methyl-N-(prop-2-yn-1-yl)benzene-1-sulfonamide | [Molecular Formula]
C10H11NO2S | [MOL File]
55022-46-3.mol | [Molecular Weight]
209.26 |
| Chemical Properties | Back Directory | [Melting point ]
76 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3)) | [Boiling point ]
333.4±52.0 °C(Predicted) | [density ]
1.209±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C, stored under nitrogen | [pka]
9.43±0.50(Predicted) | [Appearance]
White to off-white Solid |
| Hazard Information | Back Directory | [Synthesis]
Add triethylamine (9.5 mL, 70 mmol, 1.4 equivalents), followed by tosyl chloride (9.53 g) portionwise to a stirred solution of propargylamine (3.84 mL, 60 mmol) in dry dichloromethane (50 mL, 1.2 M) at 0°C under argon atmosphere. Stir the mixture overnight at room temperature. Add water (50 mL) to the mixture. Extract the aqueous layer by dichloromethane (2 × 50 mL). Dry the combined organic layers over MgSO4. Concentrate the combined organic layers under reduced pressure.
| [References]
[1]Bodinier, Florent et al. Low-valent dialkoxytitanium(ii): a useful tool for the synthesis of functionalized seven-membered ring compounds†.”Chemical Communications 29 (2021): 3603–3606.
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| Company Name: |
Henan Alpha Chemical Co., Ltd.
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| Telephone: |
0371-55055611 18137792234 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList31206/0.htm |
| Company Name: |
Bide Pharmatech Ltd.
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| Telephone: |
400-1647117 13681763483 |
| Website: |
https://www.bidepharm.com/ |
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