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55273-05-7

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55273-05-7 Structure

55273-05-7 Structure
IdentificationBack Directory
[Name]

Impromidine
[CAS]

55273-05-7
[Synonyms]

SKF-92676
Impromidine
Impromidina
Impromidinum
1-[3-(1H-Imidazol-4-yl)propyl]-3-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]guanidine
Guanidine, N-[3-(1H-imidazol-5-yl)propyl]-N'-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]-
[Molecular Formula]

C14H23N7S
[MDL Number]

MFCD00867262
[MOL File]

55273-05-7.mol
[Molecular Weight]

321.44
Chemical PropertiesBack Directory
[Boiling point ]

640.0±65.0 °C(Predicted)
[density ]

1.34±0.1 g/cm3(Predicted)
[pka]

14.15±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Impromidine (SKF 92676) is a potent agonist for histamine H2 receptor. Impromidine induces gastric mucosal blood flow and acid secretion[1][2].
[IC 50]

H2 Receptor
[References]

[1] Durant GJ, et al. Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors. Nature. 1978 Nov 23;276(5686):403-5. DOI:10.1038/276403a0
[2] McIsaac RL, et al. Gastric mucosal blood flow and acid secretory changes in man with impromidine: a new specific histamine-H2-receptor agonist. Gut. 1981 Jul;22(7):529-33. DOI:10.1136/gut.22.7.529
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