| Identification | Back Directory | [Name]
L 11204 | [CAS]
55308-64-0 | [Synonyms]
DL 204
L 11204
DL-204IT
DL-204-IT
2-(3-Ethoxyphenyl)-5,6-dihydro-s-triazolo[5,1-a]isoquinoline
2-(3-ethoxy-phenyl)-5,6-dihydro-s-triazole<5,1-a>isoquinoline
5,6-Dihydro-2-(3-ethoxyphenyl)[1,2,4]triazolo[5,1-a]isoquinoline
2-(3-Ethoxyphenyl)-5,6-dihydro[1,2,4]triazolo[5,1-a]isoquinoline | [Molecular Formula]
C18H17N3O | [MDL Number]
MFCD01678325 | [MOL File]
55308-64-0.mol |
| Chemical Properties | Back Directory | [Melting point ]
102.5°C | [Boiling point ]
433.36°C (rough estimate) | [density ]
1.1589 (rough estimate) | [refractive index ]
1.5855 (estimate) |
| Hazard Information | Back Directory | [Uses]
L11204 (DL-204-IT) is a potent inhibitor of prostaglandin metabolism. L11204 inhibits PMS-induced superovulation and reduced the number of recoverable ova in the oviducts of hamsters. L11204 also inhibits chorionic gonadotrophin-induced ovarian hypertrophy and steroidogenesi in rats. L11204 is promising for research of reproductive system disorders[1][2]. | [References]
[1] Valenzuela G, et al. Effect of inhibitors of prostaglandin synthesis and metabolism on ovum transport in the rabbit. Fertil Steril. 1977 Sep;28(9):992-7. DOI:10.1016/s0015-0282(16)42803-7
[2] Lerner L J, et al. Inhibition of superovulation and alteration of ova transportation in hamsters by prostaglandin and DL-204-IT, an anti-fertility agent[J]. Prostaglandins and Medicine, 1981, 6(4): 369-374. |
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