| Identification | Back Directory | [Name]
dimethyl (tert-butoxycarbonyl)-L-aspartate | [CAS]
55747-84-7 | [Synonyms]
Dimethyl (S)-2-(Boc-amino)succinate
N-Boc-L-aspartic acid dimethyl ester
dimethyl (tert-butoxycarbonyl)-L-aspartate
(S)-dimethyl 2-(tert-butoxycarbonylamino)succinate
N-α-(t-Butoxycarbonyl)-L-aspartic acid α,β-dimethyl ester
L-Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, dimethyl ester
L-Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 1,4-dimethyl ester | [Molecular Formula]
C11H19NO6 | [MDL Number]
MFCD04116316 | [MOL File]
55747-84-7.mol | [Molecular Weight]
261.27 |
| Chemical Properties | Back Directory | [Melting point ]
64-65 °C | [Boiling point ]
356.5±32.0 °C(Predicted) | [density ]
1.136±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [pka]
10.36±0.46(Predicted) |
| Hazard Information | Back Directory | [Synthesis]
Step 1: Dimethyl (S)-2-aminosuccinate hydrochloride (5.0 g, 25.3 mmol) was dissolved in a solvent mixture of dichloromethane (50 mL) and water (25 mL) and sodium bicarbonate (4.25 g, 50.6 mmol) was added to the system. The reaction mixture was stirred for 4 hours and then the solvent was removed by rotary evaporator. The crude product was purified by recrystallization from n-heptane to give the target compound in white solid form (5.97 g, yield: 90%). | [References]
[1] Patent: CN108148022, 2018, A. Location in patent: Paragraph 0187; 0188; 0189
[2] Acta Crystallographica Section C: Crystal Structure Communications, 2013, vol. 69, # 1, p. 82 - 86
[3] Patent: WO2013/114250, 2013, A1. Location in patent: Page/Page column 168
[4] Heterocycles, 1997, vol. 44, # 1, p. 213 - 225
[5] Tetrahedron Asymmetry, 2000, vol. 11, # 15, p. 3063 - 3068 |
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| Company Name: |
3A Chemicals
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400-668-9898 |
| Website: |
www.3achem.com |
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