| Identification | Back Directory | [Name]
Phenylmethyl methanesulfonate | [CAS]
55791-06-5 | [Synonyms]
benzyl Methanesulfonate
Phenylmethyl methanesulfonate
Methanesulfonic acid, phenylmethyl ester | [Molecular Formula]
C8H10O3S | [MDL Number]
MFCD25964568 | [MOL File]
55791-06-5.mol | [Molecular Weight]
186.23 |
| Chemical Properties | Back Directory | [Boiling point ]
98 °C(Press: 0.2 Torr) | [density ]
1.244±0.06 g/cm3(Predicted) | [storage temp. ]
Store at room temperature | [Appearance]
Light yellow to light brown Oil |
| Hazard Information | Back Directory | [Synthesis]
Phenylmethyl methanesulfonate was prepared by the reaction of Benzyl alcohol and Methanesulfonyl chloride[1]:
1.Dissolve (0.5 g, 4.6 mmol) of the benzyl alcohol in 20 ml of CH2Cl2 in a one neck round bottom flask and cool the mixture at 0 °C.
2.Add (1 eq, 4.6mmol) of triethylamine under stirring.
3.Add (1 eq, 4.6 mmol) of methane sulfonyl chloride dropwise under stirring.
4.Stir the mixture open flask for one hour and half at -15 °C.
5.Quench the reaction with 2 ml of HCl 1N and wash the solution with NaHCO3 saturated aqueous solution.
6.Extract the organic phase and wash three times with water.
7.Dry the organic phase over Na2SO4.
8.Remove the solvent under reduced pressure using a rotary evaporator.
 | [References]
[1] F. OLIVITO . Efficient synthesis of organic thioacetates in water1[J]. Organic & Biomolecular Chemistry, 2018, 16 41: Pages 7753-7759. DOI:10.1039/c8ob01896k. |
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