| Identification | Back Directory | [Name]
4-C-Hydroxymethyl-2,3-O-isopropylidene-1-O-methyl-beta-D-ribofuranose | [CAS]
55797-67-6 | [Synonyms]
Methyl 4-C-Hydroxymethyl-2,3-O-isopropylidene-b-D-ribofuranoside
4-C-Hydroxymethyl-2,3-O-isopropylidene-1-O-methyl-beta-D-ribofuranose | [Molecular Formula]
C10H18O6 | [MDL Number]
MFCD31537243 | [MOL File]
55797-67-6.mol | [Molecular Weight]
234.246 |
| Chemical Properties | Back Directory | [Melting point ]
94-95 °C (decomp)(Solv: cyclohexane (110-82-7)) | [Boiling point ]
349.3±42.0 °C(Predicted) | [density ]
1.30±0.1 g/cm3(Predicted) | [pka]
13.83±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
Methyl 4-C-hydroxymethyl-2,3-O-isopropylidene-beta-D-ribofuranoside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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