| Identification | Back Directory | [Name]
Miroprofen | [CAS]
55843-86-2 | [Synonyms]
Y-9213
Antopen
Miroprofeno
Miroprofene
Miroprofenum
OJGQFYYLKNCIJD-UHFFFAOYSA-N
2-[4-(Imidazo[1,2-a]pyridin-2-yl)phenyl]propionic acid
2-[p-(Imidazo[1,2-a]pyridin-2-yl)phenyl]propionic acid
4-Imidazo[1,2-a]pyridin-2-yl-α-methylbenzeneacetic acid
4-(Imidazo[1,2-a]pyridin-2-yl)-α-methylbenzeneacetic acid
Benzeneacetic acid, 4-imidazo[1,2-a]pyridin-2-yl-a-methyl-
Benzeneacetic acid, 4-imidazo[1,2-a]pyridin-2-yl-α-methyl- | [Molecular Formula]
C16H14N2O2 | [MDL Number]
MFCD00864366 | [MOL File]
55843-86-2.mol | [Molecular Weight]
266.29 |
| Chemical Properties | Back Directory | [Boiling point ]
409.5°C (rough estimate) | [density ]
1.1262 (rough estimate) | [refractive index ]
1.6240 (estimate) | [pka]
3.79±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
Miroprofen (Y 0213) is an orally active nonsteroidal anti-inflammatory analgesic (NSAID). Miroprofen exhibits anti-inflammatory, analgesic and anti-platelet activities[1][2][3]. | [Definition]
ChEBI: A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(imidazo[1,2-a]pyridin-2-yl)phenyl group. A non-steroidal anti-inflammatory drug that also exhibits analgesic, antipyretic and plate
et aggregation inhibition properties. | [References]
[1] Mikashima H, et al., [Inhibitory effect of 2-(4-(2-imidazo(1,2-a)pyridyl)phenyl) propionic acid (miroprofen) on platelet aggregation and prostaglandin I2 generation (author's transl)]. Yakugaku Zasshi. 1982 Jan;102(1):99-103. Japanese. PMID:7045328
[2] Sakaizumi K, et al., [Analgesic effects of miroprofen in post-extraction pain]. Shikai Tenbo. 1983 May;61(5):1021-6. Japanese. PMID:6603669
[3] Katsu M, et al., [Double blind controlled study of miroprofen in acute upper respiratory tract infections--comparison with ibuprofen]. Kansenshogaku Zasshi. 1982 May;56(5):434-53. Japanese. DOI:10.11150/kansenshogakuzasshi1970.56.434 |
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