| Identification | Back Directory | [Name]
ISOURON | [CAS]
55861-78-4 | [Synonyms]
el-187
ISOXYL
ISOURON
Isouron solution
ISOURON STANDARD
Isouron Solution,100ppm
Isouron Solution in Methanol, 100μg/mL
isouron (bsi, draft e-iso, ansi, wssa, jmaf)
3-(5-tert-butyisoxazol-3-yl)-1,1-dimethylurea
3-(5-T-BUTYL-1,2-OXAZOL-3-YL)-1,1-DIMETHYLUREA
3-(5-tert-Butyl-3-isoxazolyl)-1,1-dimethylurea
3-(5-tert-butylisoxazol-3-yl)-1,1-dimethylurea
N'-(5-tert-Butyl-3-isoxazolyl)-N,N-dimethylurea
3-[5-(1,1-Dimethylethyl)isoxazol-3-yl]-1,1-dimethylurea
n,n-dimethyl-n’-(5-(1,1-dimethylethyl)-3-isoxazolyl)-ure
n,n-dimethyl-n’-(5-(1,1-dimethylethyl)-3-isoxazolyl)urea
n’-(5-(1,1-dimethylethyl)-3-isoxazolyl)-n,n-dimethylurea
Urea, N'-[5-(1,1-dimethylethyl)-3-isoxazolyl]-N,N-dimethyl- | [Molecular Formula]
C10H17N3O2 | [MDL Number]
MFCD00274598 | [MOL File]
55861-78-4.mol | [Molecular Weight]
211.26 |
| Chemical Properties | Back Directory | [Melting point ]
116～122℃ | [Boiling point ]
350.95°C (rough estimate) | [density ]
1.1288 (rough estimate) | [refractive index ]
1.4830 (estimate) | [storage temp. ]
Sealed in dry,2-8°C | [pka]
13.44±0.70(Predicted) | [Henry's Law Constant]
7.3×104 mol/(m3Pa) at 25℃, Duchowicz et al. (2020) | [EPA Substance Registry System]
Isouron (55861-78-4) |
| Hazard Information | Back Directory | [Uses]
Isouron was used to study the importance of physiochemical properties for design of new pesticides. | [Definition]
ChEBI: Isouron is an oxazole. | [Production Methods]
Isouron would have been manufactured using the same industrial chemistry applied to other N,N disubstituted phenylurea herbicides. Its structure indicates a two stage production process: first, synthesis of the tert butyl substituted isoxazole intermediate, typically via cyclisation of appropriate beta keto precursors; second, reaction of this heterocycle with dimethylurea or a dimethylcarbamoyl chloride/isocyanate equivalent under anhydrous, base scavenged conditions. Carbamoylation is exothermic, so manufacturers used controlled temperature, inert gas blanketed reactors similar to those used for diuron and linuron. After coupling, the crude product underwent neutralisation, filtration, solvent exchange, and drying to yield technical grade isouron. | [Mechanism of action]
Inhibition of photosynthesis at photosystem II. Selective. | [Pesticide Type]
Herbicide |
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