ChemicalBook--->CAS DataBase List--->55976-95-9

55976-95-9

55976-95-9 Structure

55976-95-9 Structure
IdentificationBack Directory
[Name]

indanol dehydrogenase
[CAS]

55976-95-9
[Synonyms]

DD3
DDX
HAKRB
HA1753
AKR1C3
AKR1C3 human
indanol dehydrogenase
Prostaglandin F Synthase human
aldo-keto reductase family 1 member C3
Recombinant Human AKR1C3 Protein, His Tag
17-beta-hydroxysteroid dehydrogenase type 5
Prostaglandin F Synthase from human, Recombinant
Prostaglandin F Synthase human recombinant, expressed in E. coli, >=90% (SDS-PAGE)
Chemical PropertiesBack Directory
[storage temp. ]

-70°C
[form ]

liquid
[Specific Activity]

≥0.4μmol/mg protein
Safety DataBack Directory
[WGK Germany ]

1
[Storage Class]

10 - Combustible liquids
Hazard InformationBack Directory
[Uses]

Prostaglandin F synthase (PGF synthase) is a member of the aldo-keto reductase superfamily of proteins which catalyze the conversion of aldehydes and ketones to thier corresponding alcohols. Prostaglandin F synthase is used in cancer research since it is upregulated in many cancers such as breast and prostate cancer. PGF synthase is also used to study kidney and renal cell carcinoma .
[Biological Activity]

PGF synthase catalyzes the conversions of 4-androstene-3,17-dione to testosteroneestrone to 17β-estradiolprostaglandin H2 to PGF2α and PGD2 to 9α,11β-PGF2. Prostaglandin (PG) F2 is synthesized via three pathways .
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