| Identification | Back Directory | [Name]
AMBUPHYLLINE | [CAS]
5634-34-4 | [Synonyms]
Busylline
Bufylline
AMBUPHYLLINE
THEOPHYLLINE (AMBUPHYLLINE)
Theophylline-?aminoisobutanol
THEOPHYLLINE-2-AMINOISOBUTANOL
1,3-Dimethyl-7H-purine-2,6-dione 2-amin
2-amino-2-methylpropan-1-ol,1,3-dimethyl-7H-purine-2,6-dione
1,3-Dimethyl-7H-purine-2,6-dione 2-amino-2-methylpropan-1-ol
3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione, compound with 2-amino-2-methylpropan-1-ol (1:1) | [EINECS(EC#)]
227-077-5 | [Molecular Formula]
C11H18N5O3 | [MDL Number]
MFCD00215846 | [MOL File]
5634-34-4.mol | [Molecular Weight]
268.292 |
| Hazard Information | Back Directory | [Originator]
Butaphyllamine,Merrell Dow,US,1944 | [Uses]
Diuretic; relaxant
(smooth muscle). | [Manufacturing Process]
Equimolecular proportions of theophylline and 2-amino-2-methyl-1-propanol
are dissolved in water and the water is evaporated until crystallization is
almost complete. The crystals are filtered off and dried. The product has a
melting point of 254-256°C, softening at 245°C. It has a water solubility of
about 55%. It may be compounded in the form of tablets, for oral
administration, or may be prepared in solution for distribution in ampoules.
For the manufacture of solutions for packaging in ampoules, it is more
convenient to simply dissolve the theophylline and the butanolamine in water,
without going through the intermediate step of separating the crystalline salt. | [Brand name]
Butaphyllamine (Marion Merrell Dow). | [Therapeutic Function]
Diuretic, Smooth muscle relaxant |
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