| Identification | Back Directory | [Name]
tirotundin | [CAS]
56377-67-4 | [Synonyms]
NSC 249959
tirotundin
Tagitinin D
Tirotundine
2-Methylpropanoic acid (3aS,4R,6S,9R,10S,11aR)-dodecahydro-9-hydroxy-6,10-dimethyl-3-methylene-2-oxo-6,9-epoxycyclodeca[b]furan-4-yl ester
Propanoic acid, 2-methyl-, (3aS,4R,6S,9R,10S,11aR)-dodecahydro-9-hydroxy-6,10-dimethyl-3-methylene-2-oxo-6,9-epoxycyclodeca[b]furan-4-yl ester | [Molecular Formula]
C19H28O6 | [MDL Number]
MFCD20275050 | [MOL File]
56377-67-4.mol | [Molecular Weight]
352.42 |
| Hazard Information | Back Directory | [Uses]
Tirotundin (Tagitinin D) is a potent anti-inflammatory agent. Tirotundin inhibits the activation of NF-Kβ[1]. | [References]
[1] Rüngeler P, et al. Study of three sesquiterpene lactones from Tithonia diversifolia on their anti-inflammatory activity using the transcription factor NF-kappa B and enzymes of the arachidonic acid pathway as targets. Planta Med. 1998 Oct;64(7):588-93. DOI:10.1055/s-2006-957527 |
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