ChemicalBook--->CAS DataBase List--->565434-85-7

565434-85-7

565434-85-7 Structure

565434-85-7 Structure
IdentificationBack Directory
[Name]

CBP-501
[CAS]

565434-85-7
[Synonyms]

CBP-501
DEZJGRPRBZSAKI-KMGSDFBDSA-N
D-Arginine, 4-benzoyl-D-phenylalanyl-D-seryl-D-tryptophyl-D-seryl-2,3,4,5,6-pentafluoro-D-phenylalanyl-3-cyclohexyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-glutaminyl-D-arginyl-
[Molecular Formula]

C86H122F5N29O17
[MDL Number]

MFCD25976803
[MOL File]

565434-85-7.mol
[Molecular Weight]

1929.06
Chemical PropertiesBack Directory
[density ]

1.55±0.1 g/cm3(Predicted)
[Sequence]

d({4-Bz-Phe}-Ser-Trp-Ser-{pentafluoro-Phe}-{Cha}-Arg-Arg-Arg-Gln-Arg-Arg)
Hazard InformationBack Directory
[Uses]

CBP-501 is a cell-permeable and calmodulin-binding peptide that enhances the influx of platinum agents into tumor cells and tumor immunogenicity. CBP-501 can be utilized in cancer research[1].
[References]

[1] Enzler T, et al. A multicenter, randomized phase 2 study to establish combinations of CBP501, cisplatin and nivolumab for ≥3rd-line treatment of patients with advanced pancreatic adenocarcinoma. Eur J Cancer. 2024 Apr;201:113950. DOI:10.1016/j.ejca.2024.113950
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