| Hazard Information | Back Directory | [Uses]
Treatment of anthrax infection. | [Brand name]
ABthrax (Human Genome Sciences). | [in vivo]
Raxibacumab (150 μg/kg or 300 μg/kg for i.v., single dose) significantly improved in outcome when it was administered up to 6 h after rats initial exposure to Bacillus anthracis lethal toxin (LeTx) infusion[3].
| Animal Model: | In SD rats after the initiation of a 24-h LeTx infusion[3] | | Dosage: | 150 μg/kg or 300 μg/kg | | Administration: | At the time of or 3, 6, 9, or 12 h after the initiation of LeTx infusion, the rats were randomized to be treated i.v. in a single dose | | Result: | Significantly improved in outcome when it was administered up to 6 h (and approached significance when administered up to 12 h) after initial exposure to LeTx.
Rats receiving raxibacumab within 6 hours of toxin administration had a better survival rate than those that received raxibacumab at 9 or 12 hours.
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Biolab Reagents
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Cell Sciences
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www.cellsciences.com |
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Wonda Science
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+1 (514) 581-6866 |
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www.wondascience.com |
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