| Identification | Back Directory | [Name]
H-NVA-OME HCL | [CAS]
56558-30-6 | [Synonyms]
H-NVA-OME HCL
L-Nva-OMe·HCl
DL-Nva-OMe·HCl
NORVALINE-OME HCL
METHYL L-NORVALINATE
H-NVA-OME HCL USP/EP/BP
H-Nva-OMe hydrochloride
METHYL L-NORVALINATE HCL
L-NORVALINE METHYL ESTER HCL
Methyl norvalinate hydrochloride
Methyl L-norvalinate hydrochloride
L-NORVALINE METHYL ESTER HYDROCHLORIDE
L-2-AMINOVALERIC ACID-METHYL ESTER HCL
(S)-methyl 2-aminopentanoate hydrochloride
methyl (2S)-2-aminopentanoate hydrochloride
L-Norvaline, Methylester, hydrochloride (1:1)
(2S)-2-aminovaleric acid methyl ester hydrochloride
(S)-2-Amino-pentanoic acid methyl ester hydrochloride
(2S)-2-aminopentanoic acid methyl ester hydrochloride
L-Norvaline methyl ester hydrochloride≥ 99.9% (HPLC) | [EINECS(EC#)]
1533716-785-6 | [Molecular Formula]
C6H14ClNO2 | [MDL Number]
MFCD00190974 | [MOL File]
56558-30-6.mol | [Molecular Weight]
167.63 |
| Hazard Information | Back Directory | [Chemical Properties]
White to off-white powder | [Uses]
(S)-Methyl 2-Aminopentanoate Hydrochloride can be prepared to use as a pesticides. | [Synthesis]
L-norvaline (160 g, 1.34 mol) was dissolved in 28.5% hydrochloric acid solution (278 g) and diluted with methanol (500 ml). The reaction mixture was refluxed for 6 hours under the protection of inert atmosphere. After completion of the reaction, the solvent was removed by co-evaporation with toluene. The residue was treated with tert-butyl methyl ether (800 ml) at 50 °C. The resulting suspension was stirred at room temperature and subsequently filtered. The resulting white solid was washed with tert-butyl methyl ether to give 216 g of L-norvaline methyl ester hydrochloride in 97% yield. | [References]
[1] Angewandte Chemie, 1992, vol. 104, # 1, p. 97 - 99
[2] Synthesis, 2010, # 17, p. 2915 - 2921
[3] Patent: WO2013/136265, 2013, A1. Location in patent: Page/Page column 21-22
[4] Patent: WO2004/33434, 2004, A1. Location in patent: Page 34
[5] Heterocycles, 1998, vol. 47, # 2, p. 765 - 780 |
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