| Identification | Back Directory | [Name]
ROSAPROSTOL | [CAS]
56695-65-9 | [Synonyms]
C-83
Rosal
IBI-C83
AY-22469
ROSAPROSTOL
Rosaprostolum
Einecs 260-341-8
Rosaprostolum [latin]
ROSAPROSTOL USP/EP/BP
NMAOJFAMEOVURT-UHFFFAOYSA-N
7-(2-Hexyl-5-hydroxycyclopentyl)heptanoic acid | [EINECS(EC#)]
260-341-8 | [Molecular Formula]
C18H34O3 | [MDL Number]
MFCD00868206 | [MOL File]
56695-65-9.mol | [Molecular Weight]
298.464 |
| Hazard Information | Back Directory | [Description]
Rosaprostol is an antisecretory and cytoprotective prostaglandin analog useful in
the treatment of gastric and duodenal ulcers. Considerably less potent than
enprostil or misoprostol, it is reported to lack the typical gastrointestinal and
cardiovascular side effects of PGE derivatives. | [Chemical Properties]
Oily substance. Rosaprostol Sodium: C18H33NaO3. White solid. Acute toxicity LD50 in mice and rats (mg/kg): Approximately 3000 oral dose; >5000 oral dose. | [Originator]
Inatituto Biochemico Italiano (Italy) | [Uses]
Rosaprostol is a compound with antiulcer activity, and its enantiomers can be synthesized from the corresponding building blocks via a specific synthetic route involving multistep reactions and stereoselective transformations. | [Brand name]
ROSAL | [References]
[1] Synthesis of Enantiomerically Pure Stereomers of Rosaprostol DOI:10.1021/acs.joc.5b01749 |
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