| Identification | Back Directory | [Name]
6,7-dimethoxyphthalide | [CAS]
569-31-3 | [Synonyms]
Opianyl
Meconine
NSC 35547
Meconic lactone
6,7-dimethoxyphthalide
Noscapine Impurity 4(Meconine)
Meconin (1.0 mg/mL in Chloroform)
6,7-DiMethoxy-3H-1-isobenzofuranone
6,7-dimethoxy-3H-2-benzofuran-1-one
6,7-dimethoxy-3H-isobenzofuran-1-one
6,7-Dimethoxy-1(3H)-isobenzofuranone
6,7-Dimethoxyisobenzofuran-1(3H)-one
cyanoformic acid (phenylmethyl) ester
1(3H)-Isobenzofuranone, 6,7-dimethoxy- | [EINECS(EC#)]
209-311-8 | [Molecular Formula]
C10H10O4 | [MDL Number]
MFCD00219354 | [MOL File]
569-31-3.mol | [Molecular Weight]
194.184 |
| Chemical Properties | Back Directory | [Melting point ]
103℃ | [Boiling point ]
290.62°C (rough estimate) | [density ]
1.2534 (rough estimate) | [refractive index ]
1.5430 (estimate) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml | [form ]
A crystalline solid | [color ]
White to off-white | [Water Solubility ]
2.5g/L(25 ºC) |
| Questions And Answer | Back Directory | [Synthesis]
Compound 7 (91.0 g, 0.5 mol), HCHO solution (81 g, 1.0 mol), HCl (80 g, 0.8 mol) and AcOH (200 g) were heated at 50~60 °C for 24 h to obtain a clear solution, which was then poured into cold water Chemicalbook (1kg). The resulting solid was collected by suction filtration, washed with water (60 g x 3), and dried at 50 °C to give crude cinnamon 8 (95 g) as a tan solid, which was purified by recrystallization from 90% MeOH/H2O (180 g) ) to obtain purified Meconin.
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| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
A lactone of meconinic acid, extracted from opium. Meconin is a marker for illicit opiate use. | [Definition]
ChEBI: Meconine is a member of 2-benzofurans. | [Synthesis Reference(s)]
Tetrahedron Letters, 28, p. 3369, 1987 DOI: 10.1016/S0040-4039(00)95515-1 | [IC 50]
Human Endogenous Metabolite |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
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| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
BePharm Ltd
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| Telephone: |
400-685-9117 |
| Website: |
www.bepharm.com |
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