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571147-18-7

571147-18-7 Structure

571147-18-7 Structure
IdentificationBack Directory
[Name]

ALX 5407 HYDROCHLORIDE
[CAS]

571147-18-7
[Synonyms]

ALX 5407
FDORQEIHOKEJNX-HSZRJFAPSA-N
ALX 5407 HYDROCHLORIDE USP/EP/BP
(R)-2-((3-([1,1,-biphenyl]-4-yloxy)-3-phenylpropyl)(methyl)amino)acetic acid
N-[(3R)-3-([1,1'-Biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl]-N-methylglycine
N-[(3R)-3-([1,1'-BIPHENYL]-4-YLOXY)-3-(4-FLUOROPHENYL)PROPYL]-N-METHYLGLYCINE HYDROCHLORIDE
([(R)-3-(BIPHENYL-4-YLOXY)-3-(4-FLUORO-PHENYL)-PROPYL]-METHYL-AMINO)-ACETIC ACID HYDROCHLORIDE
GLYCINE, N-[(3R)-3-([1,1'-BIPHENYL]-4-YLOXY)-3-(4-FLUOROPHENYL)PROPYL]-N-METHYL-, HYDROCHLORIDE
ALX5407hydrochloride,N-[(3R)-3-([1,1'-Biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl]-N-methylglycinehydrochloride
[Molecular Formula]

C24H24FNO3
[MDL Number]

MFCD09971056
[MOL File]

571147-18-7.mol
[Molecular Weight]

393.45
Chemical PropertiesBack Directory
[density ]

1.45 (20 ºC)
[storage temp. ]

Desiccate at +4°C
Hazard InformationBack Directory
[Definition]

ChEBI: 2-[[(3R)-3-(4-fluorophenyl)-3-(4-phenylphenoxy)propyl]-methylamino]acetic acid is a member of biphenyls.
[Biological Activity]

Selective non-transportable inhibitor of the glycine transporter GlyT1 (IC 50 values are 3 nM and > 100 mM for human GlyT1c and GlyT2 respectively). Displays no activity at the inhibitory glycine receptor or glycine site of the NMDA receptor (IC 50 > 100 mM).
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