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572-32-7

572-32-7 Structure

572-32-7 Structure
IdentificationBack Directory
[Name]

AYANIN
[CAS]

572-32-7
[Synonyms]

AYANIN
Ayarin
NSC 691652
3,7,4'-Tri-O-methylquercetin
Quercetin 3,4',7-trimethyl ether
QUERCETIN 3,7,4'-TRIMETHYL ETHER
3',5-Dihydroxy-3,4',7-trimethoxyflavone
5,3'-Dihydroxy-3,7,4'-trimethoxyflavone
5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxychromen-4-one
2-(3-Hydroxy-4-methoxyphenyl)-3,7-dimethoxy-5-hydroxy-4H-1-benzopyran-4-one
5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxy-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one,5-hydroxy-2-(3-hydroxy-4-Methoxyphenyl)-3,7-diMethoxy-
[Molecular Formula]

C18H16O7
[MDL Number]

MFCD03844820
[MOL File]

572-32-7.mol
[Molecular Weight]

344.32
Chemical PropertiesBack Directory
[Melting point ]

173℃
[Boiling point ]

600.8±55.0 °C(Predicted)
[density ]

1.45±0.1 g/cm3(Predicted)
[storage temp. ]

4°C, protect from light
[form ]

Solid
[pka]

6.15±0.40(Predicted)
[color ]

White to yellow
[InChI]

InChI=1S/C18H16O7/c1-22-10-7-12(20)15-14(8-10)25-17(18(24-3)16(15)21)9-4-5-13(23-2)11(19)6-9/h4-8,19-20H,1-3H3
[InChIKey]

KPCRYSMUMBNTCK-UHFFFAOYSA-N
[SMILES]

C1(C2=CC=C(OC)C(O)=C2)OC2=CC(OC)=CC(O)=C2C(=O)C=1OC
Hazard InformationBack Directory
[Uses]

Ayanin is a bioflavonoid isolated from Croton schiedeanus Schlecht. Ayanin is a non-selective phosphodiesterase inhibitor.
[Definition]

ChEBI: 3',5-dihydroxy-3,4',7-trimethoxyflavone is a trimethoxyflavone that is quercetin in which the hydroxy groups at positions 3, 4' and 7 have been replaced by methoxy groups. It has a role as a plant metabolite. It is a dihydroxyflavone and a trimethoxyflavone. It is functionally related to a quercetin. It is a conjugate acid of a 3',5-dihydroxy-3,4',7-trimethoxyflavone(1-).
[Biological Activity]

Ayanin is a biologically active flavonoid isolated from Croton schiedeanus Schlecht. Ayanin is a non-selective phosphodiesterase (phosphodiesterase1-4) inhibitor, which can be used in the study of respiratory diseases, such as allergic asthma.
[in vitro]

Ayanin inhibits interleukin (IL)-4 production from purified basophils with an IC 50 value of 2.2 μM.

[target]

PDE2A

PDE4

[storage]

4°C, protect from light
Spectrum DetailBack Directory
[Spectrum Detail]

AYANIN(572-32-7)1HNMR
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