| Identification | Back Directory | [Name]
N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)pyridin-2-yl]quinazolin-4-amine | [CAS]
573678-04-3 | [Synonyms]
NGD8243
NGD-8243
NGD 8243
N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)pyridin-2-yl]quinazolin-4-amine
4-Quinazolinamine, N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)-2-pyridinyl]- | [Molecular Formula]
C21H12F6N4 | [MDL Number]
MFCD18651674 | [MOL File]
573678-04-3.mol | [Molecular Weight]
434.34 |
| Hazard Information | Back Directory | [Uses]
MK-2295 (NGD-8243) is a TRPV1 antagonist. MK-2295 is an analgesic agent, and can be used for research of pain[1][2]. | [IC 50]
TRPV1 | [References]
[1] Gunthorpe MJ, et al. Clinical development of TRPV1 antagonists: targeting a pivotal point in the pain pathway. Drug Discov Today. 2009 Jan;14(1-2):56-67. DOI:10.1016/j.drudis.2008.11.005
[2] Arthur Gomtsyan, et al. Chapter 8 - Clinical and Preclinical Experience with TRPV1 Antagonists as Potential Analgesic Agents. TRP Channels as Therapeutic Targets. From Basic Science to Clinical Use. 2015, Pages 129-144. |
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| Company Name: |
Key Organics Ltd.
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| Tel: |
+44 (0) 1840-212137 |
| Website: |
www.keyorganics.net |
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