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57452-98-9

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57452-98-9 Structure

57452-98-9 Structure
IdentificationBack Directory
[Name]

l-Praziquantel
[CAS]

57452-98-9
[Synonyms]

(R) PZQ
(R)-PZQ
Lopac-P-4668
l-Praziquantel
(-)-Pragiquantel
(R)-(-)-Praziquantel
(11bR)-2-(cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
(R)-2-(Cyclohexanecarbonyl)-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one
(11bR)-2-(Cyclohexylcarbonyl)-1,2,3,6,7,11B-Hexahydro-4H-Pyrazino[2,1-a]Isoquinolin-4-One
4H-Pyrazino[2,1-a]isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-, (R)-
4H-Pyrazino[2,1-a]isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-, (11bR)-
4H-Pyrazino[2,1-a]isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-, (11bR)- (9CI)
(R)-(-)-Praziquantel,(11bR)-2-(cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
[Molecular Formula]

C19H24N2O2
[MDL Number]

MFCD22571801
[MOL File]

57452-98-9.mol
[Molecular Weight]

312.41
Chemical PropertiesBack Directory
[Melting point ]

113-115 °C
[Boiling point ]

544.1±50.0 °C(Predicted)
[density ]

1.22±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer
[solubility ]

Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

-0.98±0.20(Predicted)
[color ]

White to Pale Yellow
Hazard InformationBack Directory
[Uses]

(R)-Praziquantel is the active enantiomer of praziquantel regarding activity against juvenile S. mansoni infestations in mice. (R)-Praziquantel exhibits Schistosoma mansoni infestation inhibition in vitro and in vivo.
[IC 50]

5-HT2B Receptor; Antischistosomal
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