57452-98-9

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57452-98-9 Structure

Identification	Back Directory
[Name] l-Praziquantel
[CAS] 57452-98-9
[Synonyms] (R) PZQ (R)-PZQ Lopac-P-4668 l-Praziquantel (-)-Pragiquantel (R)-(-)-Praziquantel (11bR)-2-(cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one (R)-2-(Cyclohexanecarbonyl)-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one (11bR)-2-(Cyclohexylcarbonyl)-1,2,3,6,7,11B-Hexahydro-4H-Pyrazino[2,1-a]Isoquinolin-4-One 4H-Pyrazino[2,1-a]isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-, (R)- 4H-Pyrazino[2,1-a]isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-, (11bR)- 4H-Pyrazino[2,1-a]isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-, (11bR)- (9CI) (R)-(-)-Praziquantel,(11bR)-2-(cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
[Molecular Formula] C19H24N2O2
[MDL Number] MFCD22571801
[MOL File] 57452-98-9.mol
[Molecular Weight] 312.41

Chemical Properties	Back Directory
[Melting point ] 113-115 °C
[Boiling point ] 544.1±50.0 °C(Predicted)
[density ] 1.22±0.1 g/cm3(Predicted)
[storage temp. ] -20°C Freezer
[solubility ] Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
[form ] Solid
[pka] -0.98±0.20(Predicted)
[color ] White to Pale Yellow

Hazard Information	Back Directory
[Uses] (R)-Praziquantel is the active enantiomer of praziquantel regarding activity against juvenile S. mansoni infestations in mice. (R)-Praziquantel exhibits Schistosoma mansoni infestation inhibition in vitro and in vivo.
[IC 50] 5-HT_2B Receptor; Antischistosomal

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