| Identification | Back Directory | [Name]
1-ALPHA-HYDROXYVITAMIND3 | [CAS]
57651-82-8 | [Synonyms]
25(Oh)d
Cyclohexanol, 3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1R,3Z)- | [Molecular Formula]
C27H44O | [MDL Number]
MFCD28963703 | [MOL File]
57651-82-8.mol | [Molecular Weight]
384.64 |
| Chemical Properties | Back Directory | [Melting point ]
135°C | [Boiling point ]
463.26°C (rough estimate) | [density ]
1.0044 (rough estimate) | [refractive index ]
1.4480 (estimate) | [storage temp. ]
4°C, away from moisture and light | [form ]
Solid | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
3-epi-Vitamin D3 (Epicholecalciferol) (Compound 4), a Vitamin D3 analogue, is a Hedgehog pathway inhibitor with an IC50 of 39.2 μM measured in U87MG cells[1]. | [References]
[1] Banerjee U, et al. Evaluation of vitamin D3 A-ring analogues as Hedgehog pathway inhibitors. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1330-4. DOI:10.1016/j.bmcl.2011.12.081 |
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