| Identification | Back Directory | [Name]
D-Alanine, N-(2,6-dimethylphenyl)-N-(2-furanylcarbonyl)-, methyl ester | [CAS]
57764-08-6 | [Synonyms]
D-Alanine, N-(2,6-dimethylphenyl)-N-(2-furanylcarbonyl)-, methyl ester | [Molecular Formula]
C17H19NO4 | [MOL File]
57764-08-6.mol | [Molecular Weight]
301.34 |
| Chemical Properties | Back Directory | [Boiling point ]
420.1±45.0 °C(Predicted) | [density ]
1.179±0.06 g/cm3(Predicted) | [pka]
1.35±0.50(Predicted) | [InChI]
InChI=1S/C17H19NO4/c1-11-7-5-8-12(2)15(11)18(13(3)17(20)21-4)16(19)14-9-6-10-22-14/h5-10,13H,1-4H3/t13-/m1/s1 | [InChIKey]
CIEXPHRYOLIQQD-CYBMUJFWSA-N | [SMILES]
C(OC)(=O)[C@@H](C)N(C1=C(C)C=CC=C1C)C(C1=CC=CO1)=O |
| Hazard Information | Back Directory | [Definition]
ChEBI: (R)-furalaxyl is a methyl N-(2,6-dimethylphenyl)-N-2-furoylalaninate that has R configuration. It is a methyl N-(2,6-dimethylphenyl)-N-2-furoylalaninate and a D-alanine derivative. It is an enantiomer of a (S)-furalaxyl. | [Production Methods]
A recent Chinese patent outlines an improved enantioselective synthesis of furalaxyl M, indicating that manufacturers begin with the same core intermediates used for racemic furalaxyl and then introduce a chiral resolution or asymmetric step to obtain the M enantiomer. The broader phenylamide manufacturing pattern involves assembling the 2,6 dimethyl N (2 methylphenyl) N (methoxyacetyl) DL alaninate framework through acylation of an aniline derivative, formation of the alaninate ester side chain, and final coupling. For furalaxyl M, the distinguishing commercial step is the enantioselective purification of the chiral centre to deliver the biologically active M isomer before formulation. | [Mechanism of action]
Systemic with protective and curative action. Disrupts fungal nucleic acid synthesis - RNA ploymerase 1 | [Pesticide Type]
Fungicide |
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