| Identification | Back Directory | [Name]
2-[1-PIPERAZINYL]QUINOLINE MALEATE SALT | [CAS]
5786-68-5 | [Synonyms]
ma1291
quipazinemeleate
quipazine maleate
QUIPAZINE DIMALEATE
QUIPAZINE MALEATE SALT
QUIPAZINE DIMALEATE SALT
1-(2-quinolyl)piperazinemaleate
2-(1-piperazinyl)quinoline maleate
2-(Piperazin-1-yl)quinoline maleate
2-(1-PIPERAZINYL)QUINOLINE DIMALEATE
2-(1-piperazinyl)-quinolinmaleate(1:1)
2-[1-PIPERAZINYL]QUINOLINE MALEATE SALT
2-(1-Piperazinyl)quinoline (2Z)-2-Butenedioate
2-(1-piperazinyl)-quinolin(z)-2-butenedioate(1:1)
2-(1-piperazinyl)quinoline(z)-2-butenedioate(1:1) | [EINECS(EC#)]
227-314-2 | [Molecular Formula]
C17H19N3O4 | [MDL Number]
MFCD00133796 | [MOL File]
5786-68-5.mol | [Molecular Weight]
329.35 |
| Chemical Properties | Back Directory | [Melting point ]
151-154℃ | [storage temp. ]
2-8°C | [solubility ]
H2O: soluble | [form ]
Solid | [Water Solubility ]
H2O: soluble
alcohol: soluble
dilute aqueous acid: soluble |
| Hazard Information | Back Directory | [Uses]
Quipazine is a non-selective serotonin receptor agonist. Quipazine increases renin release by a peripheral hemodynamic mechanism.
| [Uses]
Quipazine maleate salt has been used as a serotonin receptor agonist to study its effects on mouse models with spinal cord injury. It has also been used as a serotonin receptor agonist to study its effects on the locomotion of zebrafish. | [Uses]
Selective 5-HT-3 receptor agonist | [Biological Activity]
Selective 5-HT 3 receptor agonist. Also displays antagonist activity at peripheral 5-HT 3 receptors. [ 3 H]-Quipazine labels 5-HT 3 sites in the cortical membranes. | [Biochem/physiol Actions]
Quipazine belongs to the class of psychedelics and acts as a serotonin/5-hydroxytryptamine-2A/C receptor agonist. It also acts as an inhibitor of prolactin. | [in vivo]
Quipazine (25, 50 mg/kg, i.p., 1 h) exerts hyperactivity in rats[1].
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