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581772-30-7

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581772-30-7 Structure

581772-30-7 Structure
IdentificationBack Directory
[Name]

Cytidine, 2'-deoxy-2',5-difluoro-
[CAS]

581772-30-7
[Synonyms]

2',5-Difluoro-2'-deoxycytidine
Cytidine, 2'-deoxy-2',5-difluoro-
[Molecular Formula]

C9H11F2N3O4
[MDL Number]

MFCD28342721
[MOL File]

581772-30-7.mol
[Molecular Weight]

263.2
Chemical PropertiesBack Directory
[Boiling point ]

467.7±55.0 °C(Predicted)
[density ]

1.92±0.1 g/cm3(Predicted)
[pka]

12.84±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

2',5-Difluoro-2'-deoxycytidine, compound 13, has potent anti-HCV activity and toxicity to ribosomal RNA (rRNA)[1].
[References]

[1] Shi J, et al. Synthesis and anti-viral activity of a series of d- and l-2'-deoxy-2'-fluororibonucleosides in the subgenomic HCV replicon system. Bioorg Med Chem. 2005 Mar 1;13(5):1641-52. DOI:10.1016/j.bmc.2004.12.011
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