| Identification | Back Directory | [Name]
Platycodin D | [CAS]
58479-68-8 | [Synonyms]
Platycodin
Platycodin D ,98%
Platycodin D Standard
Platycodin D Exclusive
Platycodin D, 98%, from Platycodon grandiflorus (Jacq.) A. DC.
(4AR,5R,6aS,6bR,8aR,10R,11S,12aR,12bR,14bS)-(2S,3R,4S,5S)-3-(((2S,3R,4S,5R,6S)-5-(((1R,2S,3S,4
Olean-12-en-28-oic acid, 3-(β-D-glucopyranosyloxy)-2,16,23,24-tetrahydroxy-, O-D-apio-β-D-furanosyl-(1→3)-O-β-D-xylopyranosyl-(1→4)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl ester, (2β,3β,16α)- | [Molecular Formula]
C57H92O28 | [MDL Number]
MFCD09952590 | [MOL File]
58479-68-8.mol | [Molecular Weight]
1225.34 |
| Chemical Properties | Back Directory | [Melting point ]
approximate 217℃ (dec.) | [density ]
1.56 | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
Soluble in methanol and water | [form ]
powder | [pka]
12.76±0.70(Predicted) | [color ]
White | [Major Application]
metabolomics
vitamins, nutraceuticals, and natural products | [Cosmetics Ingredients Functions]
SKIN CONDITIONING | [InChIKey]
CYBWUNOAQPMRBA-CCDTVMMVNA-N | [LogP]
-0.690 (est) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302 | [Precautionary statements ]
P301+P312+P330 | [Safety Statements ]
24/25 | [WGK Germany ]
WGK 3 | [HS Code ]
29389090 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Chemical Properties]
White crystals, easily soluble in water, methanol, and ethanol, insoluble in low-polarity solvents such as acetone and ethyl acetate, derived from Platycodon grandiflorum. | [Uses]
Platycodin D is a known inhibitor of the proliferation of human gastric cancer cells as well as inducing apoptosis. It also causes anti-atherosclerotic. | [Definition]
ChEBI: A natural product found in Platycodon grandiflorum. | [Biological Activity]
Platycodin D elicits strong anti-cancer properties and exhibits cytotoxicity against several cancer cell lines of both in vitro and in vivo origin. It exerts anti-inflammatory and protective effects against lipopolysaccharide (LPS)-induced acute lung injury (ALI) by upregulating liver-X receptors α (LXRα) and ATP-binding cassette transporter A1 (ABCA1) signaling pathway. It also possesses protective effects against Cisplatin (CDDP)-induced nephrotoxicity in mice. |
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
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