58479-71-3

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58479-71-3 Structure

Identification	Back Directory
[Name] 5-HydroxyMethyl-2',3'-O-isopropylidene-2-thiouridine
[CAS] 58479-71-3
[Synonyms] 5-HydroxyMethyl-2',3'-O-isopropylidene-2-thiouridine 5-Hydroxymethyl-2',3'-di-O-isopropylidene-2-thiouridine 5-(Hydroxymethyl)-2',3'-O-(1-methylethylidene)-2-thiouridine Uridine, 5-(hydroxymethyl)-2',3'-O-(1-methylethylidene)-2-thio-
[Molecular Formula] C13H18N2O6S
[MDL Number] MFCD25542462
[MOL File] 58479-71-3.mol
[Molecular Weight] 330.36

Hazard Information	Back Directory
[Uses] 5-Hydroxymethyl-2',3'-O-isopropylidene-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References] [1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

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