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58479-71-3

58479-71-3 Structure

58479-71-3 Structure
IdentificationBack Directory
[Name]

5-HydroxyMethyl-2',3'-O-isopropylidene-2-thiouridine
[CAS]

58479-71-3
[Synonyms]

5-HydroxyMethyl-2',3'-O-isopropylidene-2-thiouridine
5-Hydroxymethyl-2',3'-di-O-isopropylidene-2-thiouridine
5-(Hydroxymethyl)-2',3'-O-(1-methylethylidene)-2-thiouridine
Uridine, 5-(hydroxymethyl)-2',3'-O-(1-methylethylidene)-2-thio-
[Molecular Formula]

C13H18N2O6S
[MDL Number]

MFCD25542462
[MOL File]

58479-71-3.mol
[Molecular Weight]

330.36
Chemical PropertiesBack Directory
[density ]

1.55±0.1 g/cm3(Predicted)
[pka]

6.98±0.23(Predicted)
Hazard InformationBack Directory
[Uses]

5-Hydroxymethyl-2',3'-O-isopropylidene-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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