ChemicalBook--->CAS DataBase List--->58754-46-4

58754-46-4

58754-46-4 Structure

58754-46-4 Structure
IdentificationBack Directory
[Name]

(E)-N-[2-[2-[(2S)-1-methyl-2-piperidyl]ethyl]phenyl]-3-phenyl-prop-2-e namide
[CAS]

58754-46-4
[Synonyms]

S-MPEC
iferanserin
2-Propenamide, N-[2-[2-[(2S)-1-methyl-2-piperidinyl]ethyl]phenyl]-3-phenyl-
(E)-N-[2-[2-[(2S)-1-methyl-2-piperidyl]ethyl]phenyl]-3-phenyl-prop-2-e namide
[Molecular Formula]

C23H28N2O
[MDL Number]

MFCD34469254
[MOL File]

58754-46-4.mol
[Molecular Weight]

348.48
Chemical PropertiesBack Directory
[storage temp. ]

4°C, away from moisture and light
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Iferanserin (S-MPEC) is a selective 5-HT receptor (serotonin receptor) antagonist with an affinity for 5-HT2A receptor. Iferanserin has the potential for internal hemorrhoid disease treatment[1].
[IC 50]

5-HT2A Receptor
[References]

[1] Herold A, et al. Intra-anal Iferanserin 10 mg BID for hemorrhoid disease: a prospective, randomized, double-blind, placebo-controlled trial. Clin Ther. 2012 Feb;34(2):329-40. DOI:10.1016/j.clinthera.2011.12.012
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