| Identification | Back Directory | [Name]
ETH 1001 | [CAS]
58801-34-6 | [Synonyms]
CA 1001
ETH 1001
Einecs 261-449-8
CALCIUM IONOPHORE
CALCIUM IONOPHORE I
CA 1001 - CAS 58801-34-6 - Calbiochem
FLUKABRAND SELECTOPHORE, CALCIUM*IONOPHORE I
(4R,5R)-N,N'-Bis[11-(ethoxycarbonyl)undecyl]-N,N',4,5-tetramethyl-3,6-dioxaoctanediamide
(-)-(R,R)-N,N'-[Bis(11-ethoxycarbonyl)undecyl]-N,N',4,5-tetramethyl-3,6-dioxooctanediamide
(-)-(R,R)-N,N'-BIS[11-(ETHOXYCARBONYL)UNDECYL]-N,N',4,5-TETRAMETHYL-3,5-DIOXAOCTANEDIAMIDE
(-)-(R,R)-N,N'-BIS-[11-(ETHOXYCARBONYL)UNDECYL]-N,N'-4,5-TETRAMETHYL-3,6-DIOXAOCTANEDIAMIDE
DIETHYL-N,N'-[(4R,5R)-4,5-DIMETHYL-1,8-DIOXO-3,6-DIOXAOCTAMETHYLENE]BIS(12-METHYLAMINODODECANOATE)
diethyl [R-(R*,R*)]-13,17,18,22-tetramethyl-14,21-dioxo-16,19-dioxa-13,22-diazatetratriacontanedioate
Diethyl (R-(R*,R*))-13,17,18,22-tetramethyl-14,21-dioxo-16,19-dioxa-13,22-diazatetratriacontanedioate
12,12'-[[(1R,2R)-1,2-Dimethylethylene]bis[oxymethylenecarbonyl(methylimino)]]bisdodecanoic acid diethyl ester
(17R,18R)-13,17,18,22-Tetramethyl-14,21-dioxo-16,19-dioxa-13,22-diazatetratriacontanedioic acid diethyl ester
16,19-Dioxa-13,22-diazatetratriacontanedioic acid, 13,17,18,22-tetramethyl-14,21-dioxo-, diethyl ester, (R-(R*,R*))-
16,19-Dioxa-13,22-diazatetratriacontanedioic acid, 13,17,18,22-tetramethyl-14,21-dioxo-, 1,34-diethyl ester, (17R,18R)-
ETH 1001, (-)-(R,R)-N,Nμ-Bis-[11-(ethoxycarbonyl)undecyl]-N,Nμ,4,5-tetramethyl-3,6-dioxaoctane-diamide, Diethyl N,Nμ-[(4R,5R)-4,5-dimethyl-1,8-dioxo-3,6-dioxaoctamethylene]bis(12-methylaminododecanoate) | [EINECS(EC#)]
261-449-8 | [Molecular Formula]
C38H72N2O8 | [MDL Number]
MFCD00042943 | [MOL File]
58801-34-6.mol | [Molecular Weight]
684.99 |
| Chemical Properties | Back Directory | [Boiling point ]
715.1±50.0 °C(Predicted) | [density ]
1.000±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
Soluble in DMSO | [form ]
Light yellow, translucent, highly viscous oil | [pka]
-0.52±0.70(Predicted) | [color ]
Colorless to light yellow | [BRN ]
2343275 | [InChIKey]
CJAONIOAQZUHPN-KKLWWLSJSA-N | [SMILES]
CCOC(=O)CCCCCCCCCCCN(C)C(=O)CO[C@H](C)[C@@H](C)OCC(=O)N(C)CCCCCCCCCCCC(=O)OCC |
| Hazard Information | Back Directory | [Description]
Calcium ionophore I is a Ca2+-selective ionophore for biological membranes that can be used in microelectrodes for the determination of intracellular Ca2+-activities and of slowly changing Ca2+ levels. | [Uses]
Calcium ionophore I (ETH 1001) is a selective Ca2+ ionophore for biological membranes. Calcium ionophore I can be used in Ca2+-selective microelectrodes that can be used for quantitative intracellular measurements of resting Ca2+-activities and of slowly changing Ca2+-levels[1][2]. | [storage]
Store at -20°C | [Purification Methods]
This is a neutral Ca selectophore. It can be purified by thick layer (2mm) chromatography (Kieselgel F245) and eluted with Me2CO/CHCl3 (2:1). [Ammann et al. Helv Chim Acta 56 1780 1973, Simon & Carafoli Methods Enzymol 56 439 1977.] | [References]
dagostino m, lee co. neutral carrier na+- and ca2+-selective microelectrodes for intracellular application. biophys j. 1982 dec;40(3):199-207.caroni p, gazzotti p, vuilleumier p, et al. ca2+ transport mediated by a synthetic neutral ca2+ -ionophore in biological membranes. biochim biophys acta. 1977 nov 1;470(3):437-45.hinds tr, vincenzi ff. the effect of eth 1001 on ion fluxes across red blood cell membranes. cell calcium. 1985 jun;6(3):265-79.lücke a, lehmenkühler a, speckmann ej. the influence of the convulsant pentylenetetrazol on ca2+-selective microelectrodes (neutral carrier eth 1001). j neurosci methods. 1989 aug;29(2):139-42.lee mh, yoo cl, lee js, et al. tweezer-type neutral carrier-based calcium-selective membrane electrode with drastically reduced anionic interference. anal chem. 2002 jun 1;74(11):2603-7. |
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